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Schmidlin et al., 2019

Natural Medicine Journal

Published 2024-5-30 Background: Tamoxifen is commonly used in the treatment of hormonal-positive breast cancer

SAM is a product of one-carbon metabolism cycle and is synthesized by methionine adenosyltransferase (MAT) using methionine and ATP as substrates

A similar observation was seen in L-DOPA treated wild type flies

Following this, the protein lysates were denatured in a metal bath at 95 C and subjected to SDS-polyacrylamide gel electrophoresis (SDS-PAGE) for separation