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Resistance to platinum-based drugs has seriously affected prognosis in tumor patients

Neuropharmacology 60:5865 Pradhan AA, Befort K, Nozaki C, Gavriaux-Ruff C, Kieffer BL (2011) The delta opioid receptor: an evolving target for the treatment of brain disorders

The amount of glutathione in the glutathione Sepharose 4B beads was estimated according to the assumption (according to the manufacturere's information) that there are about 200400 mol glutathione/g dried beads

Indeed, overexpression of SLC27A5 conferred the sensitivity to sorafenib treatment in resistant cells, as shown by relative cell viability, growth curves, and colony formation (Fig