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For example, if drug A ('perpetrator' drug) inhibits a membrane transporter that drug B ('victim' drug) uses to enter into the cell, administration of drug A can lower the level of drug B in the cell and also potentially increase the level of drug B in the systemic circulation

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In addition to the nucleus, activated STAT3 can also be taken up into mitochondria, where it promotes mitochondrial functionality and maintains mitochondrial membrane potential 38

Ultimately, after a treacherous incident which at first appeared to be a surrender, the Confederates ultimately surrendered after another round of gunfire

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To overcome innate and adaptive immunity, B