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Chen GY, OLeary BR, Du J, Carroll RS, Steers GJ, Buettner GR, Cullen JJ

Abati E, Bresolin N, Comi G, Corti S (2020) Silence superoxide dismutase 1 (SOD1): a promising therapeutic target for amyotrophic lateral sclerosis (ALS)

A differentiating feature of this HTC-based approach is the ability, embodied by dHTC1, to prospectively discover noncovalent molecular glues that rely on interfacial proteinprotein contacts that cooperatively stabilize a ternary complex

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Figure 1 Summarizing the above, the oxidative stress and mitochondrial dysfunction are of high importance in the pathology and pathogenesis of AD and dementia