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Furthermore, the supplementation of energy substrates, including glucose and lactate, significantly augments the energy supply of cells under hypoxic conditions, thereby ensuring the sustained maintenance of normal cellular functions and metabolic homeostasis

Resveratrol has been shown to impart chemopreventive effect by down-regulating TNF--induced activation of urokinase plasminogen activator (uPA) and uPA receptor (uPAR) mRNA, expressions resulting in the inhibition of human glioma cell invasion [135]