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doi: 10.2217/epi-2018-0162 131 Noori-ZadehAMesbah-NaminSASaboor-YaraghiAA

Microbial Dysbiosis Modulates Protein Clearance Mechanisms, Autoimmune Functions, and Central Nervous System Immune Recruitment Aggregated misfolded protein and autophagolysosomal-proteasomal pathways participate in a vicious cycle that causes cytotoxicity and exacerbates hallmark pathologies of neurodegenerative disorders (Monaco and Fraldi, 2020)

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At high glucose levels, glycolysis is dominant and glycolytic intermediates and products are utilized to generate ATP as well as lipids and amino acids