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Several intracellular proteins such as PINK1, parkin, LRRK2, and -Syn are modulated under Mn-induced neurotoxicity, suggesting that these proteins might be potential molecular targets to develop therapeutics against Mn-induced neurotoxicity

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Swedish Metabolomics Centre, Ume, Sweden (www.swedishmetabolomicscentre.se) is acknowledged for help with methodology standadization and quantification of pyroglutamic acid Kynurenine and tryptophan by LC-MS