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Importantly, NNMTi is highly selective and has no inhibitory effect on other SAM-dependent methyltransferases or NAD + salvage pathway enzymes

Suicidal behavior and ideation have been reported in clinical trials with other incretin mimetics indicated for weight management

Some diseases that affect the end of the small intestine where vitamin B12 is absorbed may affect the absorption of the vitamin - for example, Crohn's disease

References from identified articles were reviewed for additional pertinent human studies

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