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In a clinical comparison with phenazepam, Selank achieved comparable anxiety reduction without sedation, muscle relaxation, tolerance, or withdrawal syndrome

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M.BernsteinC

DDE, DDT metabolite, dichlorodiphenyl-dichloroethylene

doi: 10.3390/pr12020342

Passage of bile acids through the enterocyte activates FXR, which promotes the synthesis of fibroblast growth factor 19 (FGF19), which also circulates through the portal vein to the liver where it activates fibroblast growth factor-receptor 4 resulting in inhibition of bile acid synthesis