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It can take a few years to develop a deficiency because your body can store B12 in your liver for a long time

It is only available for prescription use and is administered by injection or, in severe cases, an IV drip

Most laboratory protocols recommend reconstituting a 30mg total mass vial with 2mL of sterile bacteriostatic water

Theres no universally best time, but most users inject: Once daily in the morning , or Split into two doses : AM and PM for more stable coverage (especially for injury or gut repair) For injury-specific cases, timing the dose post-workout or before sleep may support natural repair cycles

Adjustments to the dosage or treatment approach, might be needed depending on how the patient responds and tolerates the therapy

Cramps of pain associated with B12 deficiency-related neuropathy can happen at any time of day - or just at night. Most conditions that cause leg pain or numbness improve with rest, but symptoms that persist could be signalling an underlying deficiency