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NF-B is a key transcriptional regulator of inflammatory mediators and leads to, for example, increased expression of TNF-, IL-6, IL-8, E-selectin, VCAM-1, and ICAM-1 [166,167,168]

While excess body weight can worsen the condition,the occurrence of cellulite largely depends on genetics, diet, hormones, age, and activity level

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ADT, androgen-deprivation therapy

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