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The reasons why some cell types undergo extensive radiation-induced apoptosis within a few hours after irradiation, while others do not, remains uncertain but may relate to the relative expression and function of proteins which trigger an apoptotic response

Half-life values are derived from specific assay conditions typically IV bolus administration in a single species with healthy plasma and may not reflect the pharmacokinetics observed under different experimental circumstances

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Methylation and demethylation, which is the opposite process, basically work together to control different functions throughout the body

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[DOI] [PMC free article] [PubMed] [Google Scholar] 159.Canivenc-Lavier M.-C., Bennetau-Pelissero C