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Evidence shows that in addition to interhemispheric EEG asymmetry, insomnia had greater fronto-parietal asymmetry in the left hemisphere, particularly in slow frequency bands (delta and theta) during the REM sleep, when compared to the healthy controls 41

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An untargeted metabolomics analysis of antipsychotic use in bipolar disorder

Researchers found that p-tau217 levels in finger-prick samples closely matched standard blood tests, identifying Alzheimers-related changes in spinal fluid with 86% accuracy

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DHODH activity is essential for proliferating cells owing to their increased demand for nucleotides, and DHODH inhibition has long been studied as a therapeutic strategy in autoimmune diseases (for example, via leflunomide) and cancer, where it can lead to cell cycle arrest, DNA damage and replication stress 42,44,45