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63 By participating in the maintenance of cellular balance and the regulation of multiple physiological processes, amino acid metabolism serves a crucial role in immune function, 64 inflammation, 65 and oxidative stress management

Lille, Institut Pasteur de Lille, Lille, France Background: Systemic inflammation, triggered by bacteria or Pathogen-Associated Molecular Patterns (PAMPs), is a primary driver of acute-on-chronic liver failure (ACLF), a severe syndrome affecting patients with acutely decompensated cirrhosis (Hernaez et al., Gut , 2016)

ROS reaction with DNA may lead to mutagenesis, disruption of the cell cycle, and induction of apoptosis [8,9]

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doi: 10.1016/j.bcp.2004.07.009