glutathione glucuronidation reaction (a) and preferred chemical structures for Phase II Reactions: Glutathione Conjugation

Phase II Reactions: Glutathione Conjugation and Mercapturic Acid Formation Definition, Examples & FAQs JoVE Core General Principles of Pharmacology: Drug Metabolism Glucuronidation Assist by Functional Genomic Nutrition Drug Biotransformation Basic and Clinical Pharmacology, 13th Ed. Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial Phase II Reactions Biotransformation of Drugs

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