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That's in addition to, as mentioned by Gambit, excess alcohol causing issues with the liver which is the primary bodily store of B12

However, only 22% of the variation in MMA levels was explained by vitamin B12, estimated glomerular filtration rate, age, sex, and socioeconomic status, suggesting that other underlying disease was likely the reason for elevated MMA levels

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A blood test can determine if you have low B12 levels

But when you take your B12 supplement is important

Since compounding pharmacies create custom mixtures, the expiration dates for these versions are often sooner due to less extensive testing and unique preparation methods