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doi: 10.1093/ndt/gft446 134 SaadALambLS

In REDEFINE 2, 73.5% of CagriSema participants reached HbA1c 6.5% versus 15.9% on placebo (treatment-policy estimand)

The dosing ranges referenced are derived from preclinical research models and observational, non-clinical protocols

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Unknowns remain: Long-term exposure data Interactions with SSRIs/SNRIs, stimulants, or sedative-hypnotics Effects in high-stress vs