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This inhibition results in reduced expression of key osteogenic markers, such as alkaline phosphatase (ALP) and osteocalcin, which are essential for the proper differentiation of bone marrow-derived mesenchymal stem cells (BM-MSCs)

doi: 10.3389/ftox.2024.1376587 Received 25 January 2024 Accepted 01 July 2024 Published 12 August 2024 Volume 6 - 2024 Edited by Marcelo Dutra Arbo, Federal University of Rio Grande do Sul, Brazil Reviewed by Stacy Matthews Branch, Independent Researcher, Sarasota, FL, United States Peter Bonitatibus, Rensselaer Polytechnic Institute, United States Updates Copyright 2024 Cunningham, Kirk, Hong, Yang, Howard, Brearley, Senz-Trevizo, Krawchuck, Watt, Henderson, Dokladny, DeAguero, Escobar and Wagner