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Conclusion We show that the glutathione pools in hepatic cells and in the blood are quite insensitive to fluctuations in amino acid input and offer an explanation based on model predictions

663 While recent discussions have increasingly advocated for the adoption of MAFLD (metabolic dysfunction-associated fatty liver disease) to emphasize the role of metabolic disorders in disease pathogenesis, much of the existing literature has not incorporated this perspective

Heroin-administered mice involved in oxidative stress and exogenous antioxidant-alleviated withdrawal syndrome

Targeting neutrophils as a novel therapeutic strategy after stroke

Western blotting and RT-PCR demonstrated increased levels of CHOP and ATF6 compared to control, and although this study does not disclose whether psoralen induced additional pathways of DILI (cholestatic, mitochondrial etc.), it indicates that ER stress may be one of the mechanisms involved in psoralen-DILI