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Internalizing disorders like depression and/or anxiety Anticipatory stress and high sympathetic nervous system activity HPA adaptive response to low tissue glucose levels (dysglycemia) Sleep duration less than five hours, short sleep, or adaptive response to shift work Essential fatty acid (EFA) deficiency Other relatively common underlying etiologies of an elevated CAR are conditions which lead to hypometabolism like hypothyroid states, anemia, and eating disorders including anorexia nervosa presentations

It affects how well our cells can repair themselves

carbohydrates (5-7% dry weight) such as cellulose, pectins, glucose, fructose, and sucrose

Sparks DL, Doelle H, Chatterjee C

We make COAs accessible so researchers can review relevant batch information before purchasing whenever documentation is available

doi: 10.1006/cimm.1995.1183 25 GrimsteinCChoiYKWasserfallCHSatohMAtkinsonMABrantlyMLet al