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Furthermore, conditions like atrophic gastritis and the use of certain medications can further inhibit absorption, as cited by National Institutes of Health (NIH)

Regulation of the plastidial Fe-S assembly and transfer pathway Due to the toxicity of free Fe, the biosynthesis of Fe-S clusters has to be regulated together with Fe uptake (Balk and Schaedler, SufA1, SufB, SufC, SufD , and SufE1 genes cluster together, possibly due to their high expression in photosynthetic tissues (Balk and Schaedler, SUF genes is coordinated and that the plastidial SUF pathway and the ISC/CIA pathways might be differentially regulated