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To imitate the architecture of branched ubiquitin chains conjugated to OTUD5, i.e., distal K48 linkages branching off the proximal K29 linkages, we inserted monoubiquitins into the four K48 residues within a K29-linked tetraubiquitin, resulting in a K29/K48-linked branched octamer (Fig

"Classification, epidemiology, and natural history of myofascial pain syndrome." Curr Pain Headache Rep

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