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Tendon healing: a concise review on cellular and molecular mechanisms with a particular focus on the achilles tendon

Animal studies show that sleep deprivation enhances the expression of IL-1 and TNF- mRNA in brain regions involved in sleep regulation, including the frontal cortex, hypothalamus, hippocampus, basal forebrain, and pons in rodents [4, 9,10,11]

Trends in Cancer 3(7):506528

This suggests that targeting TET2 could be a dual weapon strategy to both improve CAR-T cell therapy outcomes and simultaneously reprogram MDSCs to weaken their suppressive influence within the TME