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1 Standardized mean differences of covariates in incident GLP-1RA compared to sulfonylureas, DPP4i, SGLT2i, a control composited of equal proportion of incident sulfonylureas, DPP4i, SGLT2i use and a control of participants who received usual care before and after weighting

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The degradation of the RD renders the active site loops within the catalytic domain of the full-length CBS in a more opened state (Supplementary Fig