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ABC transporters: ATP-binding cassette transporters

Electrochemical generation and interaction study of the nitro anion from nimesulide

[Abstract]2023 Jun 5;20(6):2864-2875

Abstract Exposure to environmental chemicals has been linked to various health disorders, including obesity, type 2 diabetes, cancer and dysregulation of the immune and reproductive systems, whereas the gastrointestinal microbiota critically contributes to a variety of host metabolic and immune functions

Indeed, NAG has demonstrated free radial scavenging, anti-inflammatory, antimicrobial, anti-tumor, and prebiotic (promoting beneficial gut bacterial growth) properties in preclinical research (Liu 2023)

These findings have important implications for developing therapeutic strategies through regulate apoptosis of keratinocytes in psoriasis, and Prx II inhibitors may be exploited as a therapeutic drug to alleviate psoriatic symptoms