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It is the primary neurotransmitter responsible for learning, memory consolidation, and sustained attention

1 Introduction Dry Eye Disease (DED) is a complex, chronic ocular surface disease arising from diverse etiologies, significantly impacting quality of life (Figure 1) (Liu et al., 2022

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Further investigations including echocardiography or other imaging modalities depend on the history and physical examination

Interestingly, single nucleotide polymorphisms in the IL-1, IL-6 and IL-10 genes have been associated with cachexia in gastrointestinal cancers ( The identification of these cytokines as central players in cachexia led to the development of therapeutic strategies focusing on their targeting (Monk et al., 2006

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