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Paris 91 (3-5), 173178

10.1007/s10787-017-0330-7 42 MasnecS.KokotA.ZlatarM.KalauzM.KunjkoK.RadicB.et al (2015)

HUVECs and NIH 3T3 cells in Roswell Park Memorial Institute (RPMI) 1640 and HaCaT in Dulbeccos Minimum Essential Medium (DMEM)/F-12 medium were cultured in the indicated media supplemented with 10% fetal bovine serum (FBS) and maintained at 37C in a humidified environment with 5% CO 2

The extent of inhibition of ACE is calculated using the E max model, where E max , the maximum extent of inhibition, is 100% and the C 50 , the concentration of the drug that produces 50% of maximum effect, is about 1 ng/mL

This bidirectional immune regulation makes Selank an immunomodulator rather than a simple immunostimulant

GHK-Cu still helps deep wrinkles through increased collagen and improved skin thickness, but expectations should be tempered