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Leukemia 13 : 18541858 Friesen C, Fulda S and Debatin KM (1997) Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells

The experiments were repeated thrice to achieve highest statistical significance

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The protein content of RCM was determined using a BCA assay kit

Quality filtered 16S rRNA sequences were clustered into operational taxonomic units (OTUs), with 97% similarity, by closed reference OTU-picking using the UCLUST algorithm and GreenGenes reference database (v13.5) as implemented in Quantitative Insights into Microbial Ecology (QIIME versions 1.6 and 1.7) [64]