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In another embodiment, an assay is a cell-based assay comprising contacting a cell expressing a membrane-bound form of NOVX protein, or a biologically-active portion thereof, on the cell surface with a test compound and determining the ability of the test compound to modulate (e.g., stimulate or inhibit) the activity of the NOVX protein or biologically-active portion thereof

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Diet, as another critical determinant, can rapidly modulate the structure and function of the microbiota, thereby exerting specific effects on the pathogenesis of IBD

The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase