For patients with primary head and neck cancers, fractionation may reduce the risk of inadvertent brain exposure and subsequent ferroptosis-induced brain injury, offering a promising approach to enhancing treatment efficacy while preserving neurological function
To determine a patients health priorities and preferences, healthcare providers can use the universal health Outcome Prioritization Tool (OPT) which is nonspecific to diseases and treatments
A 2024 study found that people with MTHFR who took 5 mg L-methylfolate daily showed significant improvement in sleep disturbances and sleep quality
Mitochondrial DNA mutations accumulated in HIV-1-infected children who have an excellent virological response when exposed to long-term antiretroviral therapy
Although the specific mechanisms of KD in the treatment of neurological diseases are still uncertain, it is inevitable that all neurological diseases could affect human health through oxidative damage, energy metabolism disorders or inflammatory reactions
Introduction Glioma is a threatening primary malignancy tumor in the central nervous system ( Recently, immunotherapy represented by PD-1/PD-L1 and CTLA-4 has shown excellent clinical effects on numerous tumors such as melanoma and non-small cell lung cancer ( The glioma immune microenvironment is composed of glioma cells, immune cells, cytokines and so on ( Ferroptosis is a form of regulated cell death driven by lipid peroxidation, a consequence of imbalance between cell metabolism and redox homeostasis ( Overview of Ferroptosis and Potential Singling Pathway in Glioma The main characteristics of ferroptosis include: cell morphology (mitochondria crista, volume reduction, and increase of membrane density)
