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This disruption occurs through multiple mechanisms, including direct androgen receptor antagonism, altered steroidogenesis, and interference with androgen-regulated gene expression patterns

The solution-phase approach is the preferred method for creating metal chalcogenides

[Abstract] Brain Res Bull

Meanwhile, Cav-1 plays an unexpected role in stabilizing ATP7A protein expression by preventing its ubiquitination and proteasomal degradation

Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE et al

In multiple myeloma, GOT1 expression was inhibited by shikonin, enhancing ferroptosis in multiple myeloma cells by promoting the release of autophagic labile iron (21)