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Cells with less than 200 and greater than 6000 unique genes were also filtered

doi: 10.1056/NEJMoa1803917

Pycnogenol has been shown to exert anti-inflammatory and antithrombotic effects (26) by inhibiting Cox-1 and Cox-2 enzymatic activity (27), both involved in the inflammatory pathway

Such heterogeneity complicates the development of universally effective therapies and underscores the need for personalized approaches, which currently face limitations due to an incomplete understanding of these individual determinants (164)