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Manufacturers may fortify certain foods, such as cereals, with the synthetic form of vitamin B12

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Occasional higher amounts are harmless, but long-term use should be medically supervised

[55] Vitamin B 12 serum levels are used to detect its deficiency, but do not distinguish its causes

High-dose oral therapy (1000 micrograms daily) can be effective even in some malabsorption states due to passive diffusion mechanisms, though this is not standard first-line practice in the UK and should follow local policy

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