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Collectively, the combination of treatment based on PDT, SDT, and CDT promoted the accumulation of highly poisonous 1 O 2 and OH, thus producing a drastically powerful anticancer effect

Correia MA (2017) Drug biotransformation

Determinants and outcome of amiodarone-associated thyroid dysfunction

Role of Glutathione in the body Glutathione is a natural substance produced by the normal human liver that works as a protective agent against chemicals and pollutants inside the body

Asc can directly capture OH, O 2 , and 1 O 2 and also to reduce H 2 O 2 to water via an ascorbate peroxidase reaction (Noctor and Foyer, 1998)

Effect of gemcitabine and nab-paclitaxel with or without hydroxychloroquine on patients with advanced pancreatic cancer: a phase 2 randomized clinical trial