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The rich polar and acidic amino acids in the L2 and L4 regions of hTYR stabilize arbutin in this area, allowing it to successfully chelate with copper ions

Following two freeze thaw cycles using solid CO 2 , the samples were sonicated 1 min on wet ice (S220 Ultra-sonicator from Covaris) and spun at 3000 g , 4 C, for 5 min

Potential sweetening agents of plant origin

Inform your doctor in advance if you are pregnant, planning to conceive or breastfeeding before using the medication

Oxidative damage of DNA generates severe mutations and adverse effects on transcription, producing an RNA more vulnerable to oxidation

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