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If acyl-carnitine abnormalities were confirmed, non-mitochondrial disorders of fatty-acid metabolism were ruled-out before a MD workup was initiated

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For individuals who consume little to no animal products, such as vegetarians and vegans, dietary intake might be insufficient

Kummen M et al (2017) Elevated trimethylamine- N -oxide (TMAO) is associated with poor prognosis in primary sclerosing cholangitis patients with normal liver function

The latter includes interaction with the AR DBD and thereby inhibiting the transcription of ARE-driven genes, the AR-HOXB13 complex conferring androgen responsiveness to genes that harbor a HOXB13-response element, and synergy with AR to enhance the transcription of genes that contain a HOX element adjacent to an ARE [79]