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Several fungi inhabiting the woody tissues were shown to be causal agents of the esca disease complex (Bertsch et al., GSTs and the ratio of GSSG to total glutathione were suggested as early indicators of the presence of the esca disease in grapevine canes (Valtaud et al., 2009

doi: 10.1038/ncb1676

SBMA on the other hand is caused by expansion of polyglutamine (CAG) repeats in the NTD and is associated with both loss and gain of AR function and results in progressive degradation of motor neurons, causing muscle weakness [31, 32]

Oncoprint of key AML genomic alterations across predicted subtypes in the BeatAML-proteomic cohort

Tesamorelin is a stabilised GHRH analog that is the only secretagogue with an FDA-approved indication, specifically for HIV-associated lipodystrophy