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Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hrthle cell tumors

Goal: Increase testosterone naturally without TRT Approach: HCG 1500-3000 IU weekly, divided into 3 injections Example: 750 IU Monday, Wednesday, Friday Adjust based on response and symptoms Expected results: Testosterone increase of 40-80% above baseline Symptom improvement in 50-80% of men Maintained fertility Limitations: Ceiling effect, can't achieve supraphysiological levels May not provide adequate testosterone for all men Requires ongoing injections Who should and shouldn't use HCG HCG offers significant benefits for appropriate candidates but isn't suitable for everyone

Hasegawa, M

NOX mediates several functions through redox signaling

It is usually worst in the first few days after injection and fades as the week progresses

Although direct measurement of hydroxyl radicals is challenging, oxidative damage can be assessed using indirect biomarkers