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Biochem Cell Arch 20:27272733 Alsadee SAA (2021) Hepato-nephroprotective role of Lepidium sativum against oxidative stress induced by dexamethasone in rats

The KYN/TRP ratio was positively correlated with the disease activity index SLEDAI [48]

The smaller peaks for (S-S) and (C-S) were still visible, however a clear trend could not be seen due to the overlap with phosphate bands: E.g ., the (S-N = O) mode could hardly be observed in the difference spectra

Unbalanced TRP degradation across the KYN pathway, accompanied by the release of potentially neurotoxic metabolites, has been already implicated in many mental illnesses (45, 49, 51)