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Upon activation by FOXO3a, LINC01480 inhibits the PI3K/AKT signaling pathway, thereby inducing apoptosis [127]

Participation of mind bomb-2 in sevoflurane anesthesia induces cognitive impairment in aged mice via modulating ferroptosis

It is theorized that the onset of aging related symptoms are a direct result of this loss of glutathione's cellular protection

(Kreuz and Fischle, 2016)

this lactate is then converted to pyruvate by lactate dehydrogenase (LDH) in neuronal mitochondria, fueling the tricarboxylic acid (TCA) cycle and contributing 3040% of neuronal ATP production