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The differentially methylated CpGs were categorized into differentially methylated regions (DMRs): 2 in the hippocampus, 12 in the amygdala, and 531 in the SCEZ

Studies have found that high-fat diets (HFDs) can induce dysbiosis in the gut microbiota of mice, subsequently triggering depression-like behaviors through the microbiota-gut-brain axis

L.ZamboniN.WestermannB.et al (2012)

J Gerontol Ser A Biol Med Sci

After centrifugation, the supernatant was collected, concentrated, re-dissolved in methanol, and subjected to HPLC to measure the free drug or conjugation drug