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The transcription of bidirectional lncRNAs is initiated from the PCGs promoters

doi: 10.1038/s43587-023-00473-3 6

CJC-1295 may upregulate IGF-1 through an increase in growth hormone, which may then bind to specific receptors on liver cells, potentially initiating a series of intracellular signaling events

In preclinical and in vitro research, Glutathione is used to investigate antioxidant defense and reactive-oxygen-species scavenging, detoxification and xenobiotic metabolism, redox signaling via the GSH/GSSG ratio, immune-cell function, neuroprotection, and hepatic and age-related research

Furthermore, in a maize cultivar with symptomless SCMV-resistance, a proteomic analysis revealed a down-regulation of two different GSTs in later phases of virus infection, pointing to a role of GSTs in establishing virus resistance at the early stages of pathogenesis (Wu et al., 2013a,b)