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Addetia A, Park YJ, Starr T, Greaney AJ, Sprouse KR, Bowen JE, et al

Chronic Kidney Disease (CKD) Studies on long-term use of Nexium by patients have shown an increased risk of chronic kidney disease, which may also lead to kidney failure, dialysis, and even need for a kidney transplant in some situations

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On the Evidence The existing in vitro and organ culture data is promising and mechanistically coherent, but the compound has not undergone large-scale randomised controlled trials

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