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Arch Dis Child Fetal Neonatal Ed

10.1016/j.cell.2013.04.023 168

The plasma peak concentration of monoethyl phthalate is achieved within 0.75-0.92 h, and monoethyl phthalate is primarily excreted via urine [1]

This receptor-mediated signaling pathway causes an elevation in the activity of tyrosinase and other enzymes involved in melanogenesis, ultimately giving rise to the hyperpigmentation typically linked to melasma [92,93]

[DOI] [PMC free article] [PubMed] [Google Scholar] Singh SP, Wahajuddin, Tewari D, Pradhan T, and Jain GK (2011b) PAMPA permeability, plasma protein binding, blood partition, pharmacokinetics and metabolism of formononetin, a methoxylated isoflavone

Indeed, electrophilic nitro-fatty acids which are formed via nitric oxide or nitrite-dependent redox reactions have been shown to exert antiinflammatory actions (Khoo and Freeman, Statements Acknowledgments Writing of this article was supported by the National Institute of Environmental Health Sciences, National Institutes of Health (RO1 Award ES016959 to Jesus A