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Conversely, the gut microbiota metabolite glycochenodeoxycholate [165] has been reported to promote ferroptosis via the TFR-ACSL4 pathway in MAFLD [165]

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DOI:10.3892/or.2018.6740 137

INTRODUCTION Dementia is a major cause of disability among the elderly, with Alzheimer disease being responsible for about 70% of cases