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However, it has certain metabolic and oxidative stress side effects on the kidney [2]

Al-Abed Y, Mitsuhashi T, Li H, Lawson JA, FitzGerald GA, Founds H, Donnelly T, Cerami A, Ulrich P, Bucala R: Inhibition of advanced glycation endproduct formation by acetaldehyde: role in the cardioprotective effect of ethanol

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But it's just how they, I guess it's how long the leaves are, what is it, fermented or do you know

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Effect of Manuka Honey on % Body Weight Gain (BWG) and Food and Water Consumption Treatment of rats with manuka honey (2.5 g/kg, p.o.) for 7 days caused a nonsignificant change in % BWG ( P = 0.782), daily food consumption ( P = 0.131), and water intake ( P = 0.058) as compared to the control rats (Table 1)