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Despite metabolic surgery being among the safest surgical procedures following the introduction of laparoscopic approaches, RYGB and sleeve gastrectomy have greater perioperative complication rates, as well as worse weight reduction and cardiometabolic outcome efficacy, in older (vs

Animal model studies provide further substantiate this mechanism, showing that inhibition of microglial activation significantly reduces the expression of IL-1 and TNF- in the brain (184), while concurrently improving cognitive impairments and fatigue-like behaviors observed following exercise (185)

Folz RJ, Crapo JD (1994) Extracellular superoxide dismutase (SOD3): tissue-specific expression, genomic characterization, and computer-assisted sequence analysis of the human EC SOD gene

However, the metabolic effects of such dietary intervention in children with ASD are poorly understood, especially in nonWestern populations with distinct dietary habits and healthcare infrastructure [23]

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