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Another randomised controlled study on the prognostic impact of the AUGMENT technique on patients with failed IVF revealed nonsignificant differences between patients who received the AUGMENT technique intervention and those who did not in terms of fertilisation rates and live birth rates of transferred embryos [130]

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Collectively, these studies highlight epigenetic regulation, involving HDACs and/or Nrf-2 nuclear translocation, as the main reported mechanisms of action for butyrate

3.3 Intestinal uric acid excretion: the role of transporters Intestinal uric acid excretion is mediated by a complex network of specific transporter systems expressed on the apical and basolateral membranes of enterocytes, which work in concert to regulate systemic uric acid levels

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