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Description

CD70_3_CCx EVQLLESGGGMVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKCLEWVSAI CD3-scFc SGSGGRTFYAESVEGRFTISRDNSKNTLFLQMNSLRAEDTAVYYCAKHDYSNY scFv PYFDYWGQGTLVTVSSGGGGSGGGGSGGGGSEIVLTQSPGTLSLSPGERATL SCRASQSVRSSYLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTL TISRLEPEDFAVYYCQQYGSSPFTFGCGTKLEIK 625

Damaged/aged proteins destined for degradation enter lysosomes within the basket (substrate-binding domain) of Hsp70.1 via chaperone-mediated autophagy (Figure 5A), and/or macroautophagy and microautophagy (Turk and Turk, 2009)