glutathione in the treatment of chronic fatty liver diseases scholar Role natural compounds non-alcoholic (NAFLD): a mechanistic approach | Egyptian Liver Journal Oxidative Stress in Non-Alcoholic Fatty

The gut microbial endocrine organ in type 2 diabetes

'Astragaloside IV (AS-IV)', 'fibrosis', 'pharmacokinetics', 'toxicity', 'bioavailability', and other keywords were used for retrieval, with relevant case reports, conference abstracts and duplicate studies being excluded

Liu SJ, Zhang JY, Li HL, Fang ZY, Wang Q, Deng HM, et al

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Pathological mediators like inducible nitric oxide synthase (iNOS) and hydrogen peroxide (H 2 O 2 ) impair the electron transport chain in M1 macrophages, leading to mitochondrial dysfunction and excessive accumulation of reactive oxygen species (ROS) and mitochondrial ROS (mtROS), which amplify inflammatory cascades and exacerbate oxidative stress [15,16,17]

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